Lew Ford is wearing No. 51. And a really big smile on his face.
Ford debuted in the majors on May 29, 2003, replacing Torii Hunter in center field and collecting a single off the Mariners' Shigetoshi Hasegawa leading off the bottom of the ninth. Hasegawa had replaced former Orioles left-hander Arthur Rhodes.
One of Ford's teammates with the Twins was current Double-A Bowie hitting coach Denny Hocking.
Ford finished 24th in in the American League MVP voting back in 2004 after hitting .299/.381/.446 with 31 doubles, four triples, 15 homers, 72 RBIs and 20 stolen bases.
Ford is here today because the Orioles needed another position player and wanted a right-handed bat. Most important, he was batting .331/.390/.550 with 11 homers and 40 RBIs in 62 games with the Tides.
"I think that's the first appeal, that he's doing real well at that level and has been doing real well for quite a while," said manager Buck Showalter. "Our people think he could help us. We'll see. Obviously, we've had a short bench with the injuries and the numbers, and hopefully we pitch well enough that we can keep a normal bench."
Showalter seems happy to share in Ford's excitement in returning to the majors.
"He came in my office today and you can tell it's a special day for him," Showalter said. "I hope tomorrow is a special day, too. This guy humbled himself, or whatever, and went to the Atlantic League and got himself back on the map and carried it over to Norfolk. If he had stayed there all year, he probably would have won the batting title. He was almost there with the at-bats.
"I don't know what else Lew could do to get an opportunity. We felt like at some point he would get a chance here if he maintained what he was doing, and he did. As Ronny (Johnson) puts it, he squares up a lot of balls at that level. How old I am, I remember when he was quite a force in the American League with Minnesota, and he's worked real hard physically to get back."
Jim Thome is on the bench again today. He's receiving treatment for neck spasms, but he wouldn't have started anyway with the Orioles facing Oakland left-hander Travis Blackley.
Thome could return to the lineup tomorrow night against Yankees right-hander Freddy Garcia.
Second baseman Brian Roberts will remain in short-season Single-A Aberdeen's lineup today, and the Orioles will decide later whether to activate him from the disabled list. Roberts apparently felt pretty good after last night's game, according to the report given to Showalter. He went 0-for-4 with a walk and a run scored, and he started a 4-6-3 double play.
Robert Andino will begin his injury-rehab assignment tonight at Triple-A Norfolk. He's expected to come off the disabled list on Tuesday and join the team in New York.
Speaking of joining the team, pitcher Tsuyoshi Wada will meet up with the Orioles in St. Petersburg, Fla. this weekend. He wants to sit on the bench during a game, so the Orioles will make sure to have a uniform for him.
Wada will get his first chance to actually watch a major league game. He's been rehabbing his surgically repaired left elbow in Sarasota.
Jason Hammel is doing well after undergoing surgery on his right knee and could begin baseball activities "shortly," Showalter said.
Showalter exchanged text messages with outfielder Nolan Reimold two days ago.
Katey Sagal will be one of the celebrities roasting Roseanne Barr.
By Anna Chan, TODAY
Oooh, it's going to get hot at the "Comedy Central Roast of Roseanne"! The network on Monday announced several of the celebs who will be taking jabs at the comedian.?
Among the stars set to give Roseanne Barr a taste of her own medicine are "Sons of Anarchy" star Katey Sagal, Sharon Stone, Carrie Fisher (aka Princess Leia) and "Robot Chicken's" Seth Green. Comedians Jeff Ross, Anthony Jeselnik and Amy Schumer will also be participating. No word yet if comedy's queen of mean Lisa Lampanelli will take on Roseanne.
"Glee's" Jane Lynch was earlier announced as the Roast Master.?"I've long fantasized of ripping?Roseanne Barr a new one," the actress said in a statement.
The "Roast" is set to tape Aug. 4, and will air Aug. 12 at 10 p.m. on Comedy Central.
Which other celebrities and comedians would you like to see take part in ripping Roseanne? Share your picks on our Facebook page!
To rent out ,with intent to earn money, such a possession or authorize someone legally to benefit from it, in any manner against some mutually agreed compensation, is Real estate Investing 101.
a prerequisite Proverbially, money begets money, but in this era of recessionary economy it is not necessarily and always like that. Real estate investment 101, also means to put your money to work and earn for you more money.
Unless due diligence is shown prior to and during the conduct of real estate investing 101, the outcome, not only may not be as desired but also may be very devastating too. Onus rests with the buyer It has to be clearly born in mind that in case of any defect, disadvantage, loss or vulnerability to loss, after buying a real estate is not a matter of concern or responsibility of the seller, and the onus of proof in case of a conflict, legally rests with the buyer ,once the deal between the two has been struck and signed. A word of caution Sometimes, quite a few careless investors have suffered lot of financial hardship, having been even bankrupt on this account. Purpose of this warning note, is not to put you off but to urge you to be well prepared beforehand Types of Real Estate Investing 101 There are different modes of Real estate investing and some are as following Hose rent Investment is renting out a house, usually against an agreed rent with or without some down payment in accordance with the legal agreement.
This type of investment is suitable for seniors or retired people who intend to develop a regular source of income from their real estate.
Industrial Investment means renting out to industry for use as stores, garages etc. Commercial Investment is renting out for office use or academic institution etc. Retail outlets: Real Estate may also be rented out for use as retail outlets where permissible under law.
REIT stands for real Estate Investment Trust and it is a sort of Real Estate to Real Estate deal. Something you must avoid One thing that must be avoided in Real Estate Investing, is to purchase a real estate in your own name as it may hurt you financially very badly in case something goes wrong on account of some unseen factor. Limited Liability Company and under proper legal advice.
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From: (real estate investing for beginners) http://realestate-investing101.org
Human rights groups filed a complaint in Paris Wednesday to urge the judiciary to probe the alleged involvement of French firm Qosmos in supplying Syria's regime with surveillance equipment.
While France condemns President Bashar Al-Assad's violent crackdown, it is vital that full information be released "on the involvement of French companies in supplying surveillance equipment to the Syrian regime," said Patrick Baudouin of the International Federation for Human Rights (FIDH).
The FIDH and the Human Rights League (LDH) said in a statement that they had jointly filed the complaint with the Paris prosecutor.
"Western companies must know that they cannot sell this type of equipment to authoritarian regimes without being held accountable," said Michel Tubiana of the LDH.
Qosmos says on its website that its core expertise is providing "technology that creates an information layer in communications networks, enabling detailed, real-time visibility into all IP (Internet Protocol) traffic as it crosses networks".
French authorities in May opened a probe into the activities of Amesys, another French technology firm, after the FIDH and LDH filed a complaint accusing it of providing surveillance equipment to Libya's now deceased strongman Moamer Kadhafi.
The equipment, the groups said, was aimed at targeting "opponents, arresting them and putting them in prison, where they were tortured".
Amesys said after the probe was announced that it "very strongly denies the accusation of 'complicity in torture' and hopes to quickly be able to inform the investigating magistrate of the reality of the case".
The company had admitted in September that it supplied Kadhafi's regime with "analysis equipment" but noted the deal was made only after Libya had improved ties with the West and that it did not operate any surveillance.
Testosterone Replacement Therapy ? why is it so controversial? by Monica Mollica ~ trainergize.com
For reasons that are not readily apparent, there appears to be a conservative political movement that opposes the use of testosterone in older men. This was clearly demonstrated by the report of the Institute of Medicine, which felt that testosterone is not yet ready for prime time and that there is still a need for studies to prove its efficacy 1. Along the same lines, the guidelines of the Endocrine Society on testosterone use in older men seem to be ultra-cautious 2 . But fortunately, there are also other, more liberal guidelines and recommendations 3-5.
?It is dangerous to be right when the government is wrong.? ? Voltaire
Probably no other medical issue has been bombarded by the influx of ?expert? views from all walks of life; from endocrinologists and psychiatrists to urological surgeons and gerontologists, from the lay press to the regulatory agencies and from the pharmaceutical to the entertainment industries. The dismal result of all this free-for all cacophony of opinions is a great deal of confusion, erroneous information and significant detriment to patients and physicians alike.
Let?s take an in-depth look at the reasons for the negative attitudes to male testosterone replacement therapy (I will cover post-menopausal testosterone replacement in an upcoming article), and the hard scientific data that refutes it?
Unsubstantiated Claim 1:
There Is Insufficient Evidence That Testosterone Is Beneficial in Older Men
Data:
Numerous placebo-controlled studies have demonstrated salutary effects testosterone therapy in older men 6-11. Testosterone therapy clearly improves sexual function (both libido, erectile and ejaculatory function) in older men 12. In addition, testosterone supplementation in borderline hypo-gonadal men increases muscle mass 13-17, decreases fat mass 14, 15, 17, and improves strength 8, 13, 16, 17. There are also data showing that testosterone replacement in older men increases bone mineral density 18, 19 (and thereby and counteracts osteoporosis), improves cognition (in both Alzheimer and non-demented elderly) 20-22 and mood 16, 20, 23, and also alleviates depression 24.
Recent studies have also shown that testosterone therapy significantly improves not only symptoms of androgen deficiency (including erectile dysfunction), but also metabolic and control (lowering of blood glucose and glycated hemoglobin (HbA1c) (from 10.4 to 8.6%) 25, while decreasing abdominal obesity 25. These beneficial effects were seen without any adverse effects on blood pressure or hematological, biochemical and lipid parameters 25. Testosterone gel also has been shown to reverse the metabolic syndrome and improve glycemic control in men with sub-normal plasma testosterone 26. The improvements in glycaemic control, insulin resistance, cholesterol and visceral adiposity seen is these studies show that testosterone therapy contributes to an overall reduction in cardiovascular risk.
It is strange that treatment of testosterone deficiency caused by classical diseases affecting the hypothalamus, pituitary, and/or testes has been accepted for decades although there were no large multicenter trials, but that that treatment of testosterone deficiency caused by aging is taboo despite overwhelming scientific data showing significant benefits. It appears that physicians and regulatory agencies are much more comfortable treating older men with questionable drugs that pose more harm than benefit in terms of both quality of life, cancer and mortality 27-47, than using testosterone, a drug that not only improves important symptoms and risk factors, but also can reverse sarcopenia and frailty 48-54 which has well-documented detrimental effects on well-being, physical independence, morbidity and mortality. This is a poster-child example of ?eminence? based medicine trumping evidence-based medicine.
Unsubstantiated Claim 2:
Testosterone Increases Prostate Cancer
Data:
The most prominent concern regarding testosterone treatment is its effect on prostate health. For decades, the concept that testosterone is ?bad for the prostate? has gone unchallenged. Even though prostate-specific antigen (PSA) levels increase in response to testosterone supplementation 55, 56, recent research shows that the longstanding fear of stimulating prostate cancer with testosterone supplementation is without scientific basis 57-59.
Mechanistic studies have shown that the development and growth of prostate cancer are much more complex than simply an excess of lack of androgens: nonsteroidal hormones (e.g., insulin, leptin, glucocorticoids and growth hormone), genetic susceptibility, inflammation and environmental factors appear to be significant contributors 60. Further, there are a number of puzzling situations. For instance, prostate cancer cell lines that requires initial stimulation by androgens to grow is eventually suppressed by them 60. More evidence for the not so clear-cut relation between testosterone and prostate cancer lies in the fact that prostate cancer occurs in older men at a time when testosterone levels have already declined to low levels 61. In addition, there is no prospective evidence that testosterone is correlated with the development of prostate cancer 62, and retrospective studies have failed to demonstrate an increase in prostate cancer in men treated with testosterone 63.
Another debate centers on the putative increased cardiovascular risk of testosterone therapy. While it is true that supra-physiological doses of testosterone, such as those administered by athletes, doe increase several risk factors for cardiovascular disease and cardiac events 64-66, this is not the case when testosterone therapy is used to restore low age-related testosterone levels to the normal range 59. To counter this, the anti-testosterone maffia often points to a study that was stopped before completion because much more adverse cardiovascular events were measured in the treatment group 67. However, the adverse cardiovascular events in this study could be explained by the pre-study high prevalence of cardiovascular risk factors within the study participants.
The adverse effects of testosterone therapy include an increase in hemoglobin and hematocrit (volume percentage (%) of red blood cells in blood) 59, 68, and a small decrease in HDL (the ?good? cholesterol) 59, 69. However, elderly men with low testosterone tend to have a low hematocrit and also frequently present with anemia (hemoglobin deficiency) 70, so this side-effect can actually be a good thing. And the hematocrit-induced increase in blood viscosity can be alleviated with fish oil 71, while the decrease in HDL can be counteracted by carbohydrate restriction 72 and/or niacin (vitamin B3, the most effective way for increasing HDL) 73, 74, and a moderately increased physical activity 75-78. It should be noted that the small HDL reduction is primarily observed with intramuscular testosterone injections 69, and not with transdermal gel preparations 79.
To the contrary, it is well documented that low testosterone levels actually increase cardiovascular disease risk 80, 81. Following the recent reevaluation of the estrogen-protection orthodoxy, empirical research has flourished into the role of androgens in cardiovascular health. Observational studies show that blood testosterone levels are consistently lower among men with cardiovascular disease 80, 81, suggesting a preventive role for testosterone therapy.
In middle-aged and older men, lower testosterone levels are associated with insulin resistance, metabolic syndrome and diabetes, and related conditions that predispose to cardiovascular disease 82. Lower testosterone levels predict cardiovascular events, such as stroke and transient ischaemic attack, in older men and are associated with higher cardiovascular and overall mortality 82. Randomized trials have even shown that testosterone supplementation in men with existing coronary artery disease can be protective against heart attack (myocardial ischaemia) 82.
Unsubstantiated Claim 4:
Andropause doesn?t exist
Data:
While andropause, the progressive decline in testosterone production in aging men, unquestionably does exist and warrants treatment, whether the term ?andropause? per see is a good descriptor for this phenomenon has been debated.
The terms ?andropause? or ?male menopause? are not completely accurate because androgen secretion does not cease altogether, as the term ?pause? indicates 83, 84. The term menopause is correct in that in women the reproductive cycle invariably ends with ovarian failure and an abrupt cessation of estrogen production and onset of symptoms. In men however, the reduction in testosterone levels is a gradual process and the appearance of its clinical manifestations is more subtle and develop over time. This has unfortunately led to a tendency among many suffering older men to ignore the symptoms and accept it as an unavoidable and untreatable result of aging. In a survey of health care professionals, half reported that their patients rarely or never asked about low testosterone 85. Several prominent scientists have strongly recommended that awareness of andropause and its consequences be increased 83, 86, 87.
The term ?male climacteric? is more appropriate as it suggests a decline and not a precipitous drop in hormones levels 88. The term ?male climacteric? refers to the syndrome of endocrine, somatic, and psychic changes that occur in normal men with aging. This term is good in that it emphasizes the multidimensional nature of age-related changes, including age-related decreases in other important hormones such as growth hormone (GH), insulin-like growth factor-1 (IGF-1), dehydroepiandrosterone (DHEA), and melatonin 89-91, and not only relates aspects of the male aging syndrome specifically with testosterone levels.
Andropause has also been referred to by some medical professionals as ?androgen deficiency in the aging male (ADAM),? ?partial androgen deficiency in the aging male (PADAM),? or ?aging-associated androgen deficiency (AAAD)? 84. However, andropause is the term that is used commonly by experts in the field and by lay persons alike because it retains some analogy to the term menopause in women 83. After all, what?s in a name?
Unsubstantiated Claim 5:
Estrogen replacement in post-menopausal women turned out to be bad, and therefore testosterone replacement in men must also be bad.
Reality:
This claim is screams irrational logic and an unwarranted extrapolation.
Unsubstantiated Claim 6:
Bad Kharma: It?s All about Sex
Reality:
Testosterone therapy is a touchy topic because it improves sexual capacity and enjoyment. Even in the times of Viagra, attitudes to sex remain embarrassingly silly ?imagine if you give an older man testosterone, he may want to have sex!!? The use of testosterone in women is facing a similar issue 92-95.
Unsubstantiated Claim 7:
If testosterone becomes mainstream treatment in elderly it will become abused by younger adults
Reality:
Abuse of testosterone will occur whether or not it is available for older men.
Conclusion
Testosterone deficiency in older men (hypogonadism) is very common 52, 96, 97 (up to 50% of men over the age of 50 are deficient in free testosterone when compared with peak morning concentrations in young men 91), and yet only a small proportion of hypogonadal men are receiving testosteone replacement therapy 98. In the end, a particular political viewpoint is in the eye of the beholder. Nevertheless, it is obvious that the political climate is working against testosterone replacement therapy in older men despite overwhelming scientific data supporting this appropriate pursuit as a strategy to prolong healthy longevity.
www.trainergize.com
About the Author: ?????????????
Monica Mollica has a Bachelor?s and Master?s degree in Nutrition from the University of Stockholm, Sweden, and is an ISSA Certified Personal Trainer. She works a dietary consultant, health journalist and writer for www.BrinkZone.com, and is also a web designer and videographer.
Monica has admired and been fascinated by muscular and sculptured strong athletic bodies since childhood, and discovered bodybuilding as an young teenager. Realizing the importance of nutrition for maximal results in the gym, she went for a BSc and MSc with a major in Nutrition at the University.
During her years at the University she was a regular contributor to the Swedish bodybuilding magazine BODY, and she has published the book (in Swedish) ?Functional Foods for Health and Energy Balance?, and authored several book chapters in Swedish publications.
It was her insatiable thirst for knowledge and scientific research in the area of bodybuilding and health that brought her to the US. She has completed one semester at the PhD-program ?Exercise, Nutrition and Preventive Health? at Baylor University Texas, at the department of Health Human Performance and Recreation, and worked as an ISSA certified personal trainer. Today, Monica is sharing her solid experience by doing dietary consultations and writing about topics related to health, fitness, bodybuilding, anti-aging and longevity.
References:
1. Theisen C. IOM report targets testosterone therapy. Journal of the National Cancer Institute. 2004;96(4):259.
2. Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline. The Journal of clinical endocrinology and metabolism. 2006;91(6):1995-2010.
3. Nieschlag E, Swerdloff R, Behre HM, et al. Investigation, treatment and monitoring of late-onset hypogonadism in males. The aging male : the official journal of the International Society for the Study of the Aging Male. 2005;8(2):56-58.
4. Asthana S, Bhasin S, Butler RN, et al. Masculine vitality: pros and cons of testosterone in treating the andropause. The journals of gerontology Series A, Biological sciences and medical sciences. 2004;59(5):461-465.
5. Bain J, Brock G, Kuzmarov I. Canadian Society for the Study of the Aging Male: response to health Canada?s position paper on testosterone treatment. The journal of sexual medicine. 2007;4(3):558-566.
6. Isidori AM, Giannetta E, Greco EA, et al. Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysis. Clinical endocrinology. 2005;63(3):280-293.
7. Isidori AM, Giannetta E, Gianfrilli D, et al. Effects of testosterone on sexual function in men: results of a meta-analysis. Clinical endocrinology. 2005;63(4):381-394.
8. Ottenbacher KJ, Ottenbacher ME, Ottenbacher AJ, et al. Androgen treatment and muscle strength in elderly men: A meta-analysis. Journal of the American Geriatrics Society. 2006;54(11):1666-1673.
9. Morley JE, Perry HM, 3rd, Kaiser FE, et al. Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study. Journal of the American Geriatrics Society. 1993;41(2):149-152.
10. Sih R, Morley JE, Kaiser FE, et al. Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial. The Journal of clinical endocrinology and metabolism. 1997;82(6):1661-1667.
11. Tenover JS. Effects of testosterone supplementation in the aging male. The Journal of clinical endocrinology and metabolism. 1992;75(4):1092-1098.
12. Khera M, Bhattacharya RK, Blick G, et al. Improved sexual function with testosterone replacement therapy in hypogonadal men: real-world data from the Testim Registry in the United States (TRiUS). The journal of sexual medicine. 2011;8(11):3204-3213.
13. Giannoulis MG, Martin FC, Nair KS, et al. Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? Endocrine reviews. 2012;33(3):314-377.
14. Wittert GA, Chapman IM, Haren MT, et al. Oral testosterone supplementation increases muscle and decreases fat mass in healthy elderly males with low-normal gonadal status. The journals of gerontology Series A, Biological sciences and medical sciences. 2003;58(7):618-625.
15. Snyder PJ, Peachey H, Hannoush P, et al. Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age. The Journal of clinical endocrinology and metabolism. 1999;84(8):2647-2653.
16. Wang C, Eyre DR, Clark R, et al. Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men?a clinical research center study. The Journal of clinical endocrinology and metabolism. 1996;81(10):3654-3662.
17. Bhasin S. Testosterone supplementation for aging-associated sarcopenia. The journals of gerontology Series A, Biological sciences and medical sciences. 2003;58(11):1002-1008.
18. Snyder PJ, Peachey H, Hannoush P, et al. Effect of testosterone treatment on bone mineral density in men over 65 years of age. The Journal of clinical endocrinology and metabolism. 1999;84(6):1966-1972.
19. Katznelson L, Finkelstein JS, Schoenfeld DA, et al. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. The Journal of clinical endocrinology and metabolism. 1996;81(12):4358-4365.
20. Lu PH, Masterman DA, Mulnard R, et al. Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men. Archives of neurology. 2006;63(2):177-185.
21. Cherrier MM, Matsumoto AM, Amory JK, et al. Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment. Neurology. 2005;64(12):2063-2068.
22. Azad N, Pitale S, Barnes WE, et al. Testosterone treatment enhances regional brain perfusion in hypogonadal men. The Journal of clinical endocrinology and metabolism. 2003;88(7):3064-3068.
23. Wang C, Alexander G, Berman N, et al. Testosterone replacement therapy improves mood in hypogonadal men?a clinical research center study. The Journal of clinical endocrinology and metabolism. 1996;81(10):3578-3583.
24. Pope HG, Jr., Cohane GH, Kanayama G, et al. Testosterone gel supplementation for men with refractory depression: a randomized, placebo-controlled trial. The American journal of psychiatry. 2003;160(1):105-111.
25. Boyanov MA, Boneva Z, Christov VG. Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency. The aging male : the official journal of the International Society for the Study of the Aging Male. 2003;6(1):1-7.
26. Heufelder AE, Saad F, Bunck MC, et al. Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone. Journal of andrology. 2009;30(6):726-733.
27. Plonk WM, Jr. Most would fail to benefit from JUPITER Intervention. Journal of the American College of Cardiology. 2009;54(8):744; author reply 744-745.
28. Hakansson J. [The JUPITER study poses more questions than answers]. Lakartidningen. 2009;106(26-27):1757.
29. Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet. 2002;360(9346):1623-1630.
30. Silva MA, Swanson AC, Gandhi PJ, et al. Statin-related adverse events: a meta-analysis. Clinical therapeutics. 2006;28(1):26-35.
31. Sakaeda T, Kadoyama K, Okuno Y. Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system. PloS one. 2011;6(12):e28124.
32. Bassuk SS, Wypij D, Berkman LF. Cognitive impairment and mortality in the community-dwelling elderly. American journal of epidemiology. 2000;151(7):676-688.
33. Frisoni GB, Fratiglioni L, Fastbom J, et al. Mortality in nondemented subjects with cognitive impairment: the influence of health-related factors. American journal of epidemiology. 1999;150(10):1031-1044.
34. Guralnik JM, Ferrucci L, Pieper CF, et al. Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. The journals of gerontology Series A, Biological sciences and medical sciences. 2000;55(4):M221-231.
35. Guralnik JM, Ferrucci L, Simonsick EM, et al. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. The New England journal of medicine. 1995;332(9):556-561.
36. King DS, Wilburn AJ, Wofford MR, et al. Cognitive impairment associated with atorvastatin and simvastatin. Pharmacotherapy. 2003;23(12):1663-1667.
37. Muldoon MF, Barger SD, Ryan CM, et al. Effects of lovastatin on cognitive function and psychological well-being. The American journal of medicine. 2000;108(7):538-546.
38. Orsi A, Sherman O, Woldeselassie Z. Simvastatin-associated memory loss. Pharmacotherapy. 2001;21(6):767-769.
39. Pasternak RC, Smith SC, Jr., Bairey-Merz CN, et al. ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins. Stroke; a journal of cerebral circulation. 2002;33(9):2337-2341.
40. Penninx BW, Ferrucci L, Leveille SG, et al. Lower extremity performance in nondisabled older persons as a predictor of subsequent hospitalization. The journals of gerontology Series A, Biological sciences and medical sciences. 2000;55(11):M691-697.
41. Schatz IJ, Masaki K, Yano K, et al. Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study. Lancet. 2001;358(9279):351-355.
42. Smits CH, Deeg DJ, Kriegsman DM, et al. Cognitive functioning and health as determinants of mortality in an older population. American journal of epidemiology. 1999;150(9):978-986.
43. Wagstaff LR, Mitton MW, Arvik BM, et al. Statin-associated memory loss: analysis of 60 case reports and review of the literature. Pharmacotherapy. 2003;23(7):871-880.
44. Weverling-Rijnsburger AW, Blauw GJ, Lagaay AM, et al. Total cholesterol and risk of mortality in the oldest old. Lancet. 1997;350(9085):1119-1123.
45. Brescianini S, Maggi S, Farchi G, et al. Low total cholesterol and increased risk of dying: are low levels clinical warning signs in the elderly? Results from the Italian Longitudinal Study on Aging. Journal of the American Geriatrics Society. 2003;51(7):991-996.
46. Curtis LH, Ostbye T, Sendersky V, et al. Inappropriate prescribing for elderly Americans in a large outpatient population. Archives of internal medicine. 2004;164(15):1621-1625.
47. Gottlieb S. Inappropriate drug prescribing in elderly people is common. BMJ. 2004;329(7462):367.
48. Baumgartner RN, Waters DL, Gallagher D, et al. Predictors of skeletal muscle mass in elderly men and women. Mechanisms of ageing and development. 1999;107(2):123-136.
49. Kohn FM. Testosterone and body functions. The aging male : the official journal of the International Society for the Study of the Aging Male. 2006;9(4):183-188.
50. Morley JE. Anorexia, sarcopenia, and aging. Nutrition. 2001;17(7-8):660-663.
51. Morley JE, Haren MT, Rolland Y, et al. Frailty. The Medical clinics of North America. 2006;90(5):837-847.
52. van den Beld AW, de Jong FH, Grobbee DE, et al. Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. The Journal of clinical endocrinology and metabolism. 2000;85(9):3276-3282.
53. Lang PO, Michel JP, Zekry D. Frailty syndrome: a transitional state in a dynamic process. Gerontology. 2009;55(5):539-549.
54. Kovacheva EL, Hikim AP, Shen R, et al. Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways. Endocrinology. 2010;151(2):628-638.
55. Gerstenbluth RE, Maniam PN, Corty EW, et al. Prostate-specific antigen changes in hypogonadal men treated with testosterone replacement. Journal of andrology. 2002;23(6):922-926.
56. Srinivas-Shankar U, Roberts SA, Connolly MJ, et al. Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. The Journal of clinical endocrinology and metabolism. 2010;95(2):639-650.
57. Morgentaler A. Testosterone and prostate cancer: an historical perspective on a modern myth. European urology. 2006;50(5):935-939.
58. Shabsigh R, Crawford ED, Nehra A, et al. Testosterone therapy in hypogonadal men and potential prostate cancer risk: a systematic review. International journal of impotence research. 2009;21(1):9-23.
59. Fernandez-Balsells MM, Murad MH, Lane M, et al. Clinical review 1: Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis. The Journal of clinical endocrinology and metabolism. 2010;95(6):2560-2575.
60. Morales A. The use of hormonal therapy in ?andropause?: the pro side. Canadian Urological Association journal = Journal de l?Association des urologues du Canada. 2008;2(1):43-46.
61. Morley JE. Testosterone treatment in older men: effects on the prostate. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2000;6(2):218-221.
62. Eaton NE, Reeves GK, Appleby PN, et al. Endogenous sex hormones and prostate cancer: a quantitative review of prospective studies. British journal of cancer. 1999;80(7):930-934.
63. Hajjar RR, Kaiser FE, Morley JE. Outcomes of long-term testosterone replacement in older hypogonadal males: a retrospective analysis. The Journal of clinical endocrinology and metabolism. 1997;82(11):3793-3796.
64. Hartgens F, Kuipers H. Effects of androgenic-anabolic steroids in athletes. Sports Med. 2004;34(8):513-554.
65. Hall RC. Abuse of supraphysiologic doses of anabolic steroids. Southern medical journal. 2005;98(5):550-555.
66. Foster ZJ, Housner JA. Anabolic-androgenic steroids and testosterone precursors: ergogenic aids and sport. Current sports medicine reports. 2004;3(4):234-241.
67. Basaria S, Coviello AD, Travison TG, et al. Adverse events associated with testosterone administration. The New England journal of medicine. 2010;363(2):109-122.
68. Calof OM, Singh AB, Lee ML, et al. Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials. The journals of gerontology Series A, Biological sciences and medical sciences. 2005;60(11):1451-1457.
69. Whitsel EA, Boyko EJ, Matsumoto AM, et al. Intramuscular testosterone esters and plasma lipids in hypogonadal men: a meta-analysis. The American journal of medicine. 2001;111(4):261-269.
70. Bhatia V, Chaudhuri A, Tomar R, et al. Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes. Diabetes care. 2006;29(10):2289-2294.
71. Woodcock BE, Smith E, Lambert WH, et al. Beneficial effect of fish oil on blood viscosity in peripheral vascular disease. Br Med J (Clin Res Ed). 1984;288(6417):592-594.
72. Hauner H, Bechthold A, Boeing H, et al. Evidence-based guideline of the German Nutrition Society: carbohydrate intake and prevention of nutrition-related diseases. Annals of nutrition & metabolism. 2012;60 Suppl 1:1-58.
73. Bodor ET, Offermanns S. Nicotinic acid: an old drug with a promising future. British journal of pharmacology. 2008;153 Suppl 1:S68-75.
74. Vosper H. Niacin: a re-emerging pharmaceutical for the treatment of dyslipidaemia. British journal of pharmacology. 2009;158(2):429-441.
75. Sunami Y, Motoyama M, Kinoshita F, et al. Effects of low-intensity aerobic training on the high-density lipoprotein cholesterol concentration in healthy elderly subjects. Metabolism: clinical and experimental. 1999;48(8):984-988.
76. King AC, Haskell WL, Young DR, et al. Long-term effects of varying intensities and formats of physical activity on participation rates, fitness, and lipoproteins in men and women aged 50 to 65 years. Circulation. 1995;91(10):2596-2604.
77. Blumenthal JA, Emery CF, Madden DJ, et al. Effects of exercise training on cardiorespiratory function in men and women older than 60 years of age. The American journal of cardiology. 1991;67(7):633-639.
78. Despres JP, Tremblay A, Moorjani S, et al. Long-term exercise training with constant energy intake. 3: Effects on plasma lipoprotein levels. International journal of obesity. 1990;14(1):85-94.
79. Snyder PJ, Peachey H, Berlin JA, et al. Effect of transdermal testosterone treatment on serum lipid and apolipoprotein levels in men more than 65 years of age. The American journal of medicine. 2001;111(4):255-260.
80. Liu PY, Death AK, Handelsman DJ. Androgens and cardiovascular disease. Endocrine reviews. 2003;24(3):313-340.
81. Kaushik M, Sontineni SP, Hunter C. Cardiovascular disease and androgens: a review. International journal of cardiology. 2010;142(1):8-14.
82. Yeap BB. Androgens and cardiovascular disease. Current opinion in endocrinology, diabetes, and obesity. 2010;17(3):269-276.
83. Matsumoto AM. Andropause: clinical implications of the decline in serum testosterone levels with aging in men. The journals of gerontology Series A, Biological sciences and medical sciences. 2002;57(2):M76-99.
84. Morales A, Heaton JP, Carson CC, 3rd. Andropause: a misnomer for a true clinical entity. The Journal of urology. 2000;163(3):705-712.
85. Anderson JK, Faulkner S, Cranor C, et al. Andropause: knowledge and perceptions among the general public and health care professionals. The journals of gerontology Series A, Biological sciences and medical sciences. 2002;57(12):M793-796.
86. Morley JE. Drugs, aging, and the future. The journals of gerontology Series A, Biological sciences and medical sciences. 2002;57(1):M2-6.
87. Morley JE. Andropause: is it time for the geriatrician to treat it? The journals of gerontology Series A, Biological sciences and medical sciences. 2001;56(5):M263-265.
88. Gould DC, Petty R, Jacobs HS. For and against: The male menopause?does it exist? BMJ. 2000;320(7238):858-861.
89. Morley JE, Kaiser F, Raum WJ, et al. Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone. Proceedings of the National Academy of Sciences of the United States of America. 1997;94(14):7537-7542.
90. van den Beld AW, Lamberts SW. The male climacterium: clinical signs and symptoms of a changing endocrine environment. The Prostate Supplement. 2000;10:2-8.
91. Lamberts SW, van den Beld AW, van der Lely AJ. The endocrinology of aging. Science. 1997;278(5337):419-424.
92. Morley JE, Perry HM, 3rd. Androgens and women at the menopause and beyond. The journals of gerontology Series A, Biological sciences and medical sciences. 2003;58(5):M409-416.
93. Bolour S, Braunstein G. Testosterone therapy in women: a review. International journal of impotence research. 2005;17(5):399-408.
94. Davis SR, Burger HG. Use of androgens in postmenopausal women. Current opinion in obstetrics & gynecology. 1997;9(3):177-180.
95. Rivera-Woll LM, Papalia M, Davis SR, et al. Androgen insufficiency in women: diagnostic and therapeutic implications. Human reproduction update. 2004;10(5):421-432.
96. Harman SM, Metter EJ, Tobin JD, et al. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. The Journal of clinical endocrinology and metabolism. 2001;86(2):724-731.
97. Morley JE. Androgens and aging. Maturitas. 2001;38(1):61-71; discussion 71-63.
98. Tariq SH. Knowledge about low testosterone in older men. The journals of gerontology Series A, Biological sciences and medical sciences. 2003;58(4):382-383.
Much like the mortgage market, the market for private student loans has gone through a big boom and a messy bust. Some banks and lenders played fast and loose with student loans, aggressively marketing them to borrowers who couldn?t afford that amount of debt, according to a new government report.
?Borrowers who took out loans at the height of the boom are still suffering from those excesses,? said Consumer Financial Protection Bureau Director Richard Cordray in remarks to reporters on Thursday. The report, released jointly by the U.S. Department of Education and the CFPB, is the government?s first major study of the murky private student loan market, for which there has long been little regulation or reliable data.
?American borrowers currently owe more than $150 billion in private student loans, according to the report. Default rates soared in the years since the financial crisis, and more than $8 billion in private loans are in default.
In the run-up to the financial crisis in 2008, the boom in risky private student loans was fueled by Wall Street investors? demand for securities backed by bundles of student loans, the report said. See the below graph, which draws from proprietary loan data collected from major lenders:
After the crisis, investor interest in all manner of loan-backed securities ? including student-loan-backed securities ? collapsed. And with less packaging and reselling of loans to fund the creation of new loans, the private student loan market has since dialed back and raised its lending criteria.
The result: private loans are now much harder for borrowers to get.
According to the report, more than 90 percent of the dollar amount of private student loans originated last year were co-signed ? so if the primary borrower is unable to repay the loan, the cosigner will also be responsible for payment. That?s up from 55 percent in 2005.
Much of what the report describes ? private student loans originated by financial firms often for immediate sale and securitization ? is helpful context for understanding the quandary of many borrowers and their cosigners.
In June, we detailed the plight of Francisco Reynoso, a gardener in California who cosigned on several private student loans for his son between 2005 and 2007 ? in the very heyday of the lending boom. His son later died in a car accident and now the bereaved father is saddled with the debt. Since his debt was resold times over, its not even clear to whom Reynoso owes the money may appeal to for forgiveness.
?For the relatively high number of [private student loan] borrowers currently having difficulty with repayment, it is hard to avoid default and equally hard to escape it, as compared to options available to federal borrowers,? the report explains.
Federal loans offer more flexibility and protections than most private loans?such as deferral and forbearance options or lenient repayment plans for low-income borrowers. Federal loans also are discharged if the borrower dies or suffer permanent disability. (See our reporting on the federal system for disability discharges.)
Some private student lenders, within the past year, have started to offer fixed-rate student loans, touting interest rates that are in some cases competitive with federal rates. But as Education Department and CFPB officials note, these loans are only a good deal for borrowers with exceptional credit who can qualify for the lowest interest rates and are willing to forgo the additional protections offered by federal loans.
Check out the full report. And if you?re a borrower who sees your own student loan story mirrored in this report, email us at education@propublica.org to let us know.
You can also check out the CFPB?s new tool if you?re struggling with your loan payments, or file a complaint with the agency for problems specific to private student loans.
Madfinger Games has caused quite a stir in the Android community today, when they blamed "unbelievably high" piracy rates for changing the cost of Dead Trigger from $0.99 to free. They give no solid figures, other than "soooo giant" and many are questioning their reasoning. We're not going to discuss that here tonight, but Phil has a few thoughtful questions about the lack of numbers if you want to go down that rabbit hole and join the discussion. We want to talk about piracy and Android.
I've said before, a big part of the reason people steal apps is because they have no choice. When you see all the reviews about great apps on Android, and they aren't available in your country, you have no other option many times. Of course, some folks just steal apps because they don't want to pay for them. Piracy happens, it's just not a good thing for developers.
So, here we are, 100-percent anonymous. Have you ever pirated an Android app? The poll's below -- you know what to do.
Researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital have identified several gene mutations responsible for the most common childhood brain tumor, called medulloblastoma, adding evidence to the theory that the diagnosis is a group of genetically distinct cancers with different prognoses. These and accompanying findings are likely to lead to less-toxic, better-targeted treatment approaches over the next two years, the researchers said.
"We tend to treat all medulloblastomas as one disease without taking into account how heterogeneous the tumors are at the molecular level," said Yoon-Jae Cho, MD, an assistant professor of neurology and neurological sciences at Stanford, a pediatric neurologist at Packard Children's and the senior author of the new research. "This paper represents a finer-grained view of the genetic landscape of these tumors and provides us with some leads on how to develop new therapies."
The research, which will appear online in Nature July 22, is part of a large, ongoing effort to characterize genetic errors in medulloblastoma. Two companion studies on which Cho is a co-author will be published simultaneously with his paper. The three papers came from a consortium that involves scientists at Stanford, Packard Children's, the Broad Institute, Children's Hospital Boston, the Dana-Farber Cancer Institute, the German Cancer Research Center, Brandeis University and the Hospital for Sick Children in Toronto.
Current treatment for medulloblastoma, which originates in the cerebellum and affects about 250 U.S. children each year, begins with surgery to remove as much of the tumor as possible. Patients then receive a combination of radiation and chemotherapy, but the treatments are not tailored to the tumor's genetic characteristics.
Cho's team extracted DNA from 92 medulloblastoma tumors and compared it with DNA from matched blood samples from the same patients, uncovering 12 significant "point mutations" ? single-letter errors in the genetic code ? that occurred frequently in the brain cancer. A handful of the mutations had been previously identified in smaller studies of medulloblastoma, but several mutations were novel in both medulloblastoma and in cancer.
Among the newly identified mutations was one in an RNA helicase gene, DDX3X, which Cho said is the second-most common mutation in medulloblastoma tumors. "Mutations in this gene have now also been identified in other tumor types, such as chronic lymphocytic leukemia, and head and neck tumors," he said.
However, the researchers found that it was rare for the same gene mutated in several different patients' tumors. More commonly, mutations involving a set of genes regulating a single biological pathway were found in the tumors ? a pattern that is emerging across cancer genome sequencing efforts.
Though no single tumor in the study carried all 12 mutations, the researchers were able to categorize the tumors according to which mutations they possessed. "We now understand that there are certain tumors with particular genetic signatures that are really resistant to standard treatments," Cho said. Children with medulloblastoma do not routinely have their tumors' genetic signatures characterized, but Cho believes that such characterization coupled with targeted therapies could greatly enhance tumor treatment.
About two-thirds of medulloblastoma patients now survive five years past diagnosis, but many survivors suffer lasting physical or intellectual side effects from their cancer treatments. Drugs tailored to a tumor's genetic profile have the potential to save more patients while reducing side effects, Cho said.
Several of the mutations discovered affect cellular signals that switch large groups of genes on and off. "The dysregulation of these 'epigenetic programs' is becoming a common theme not only in medulloblastoma but across cancer," Cho said. Such pathways may be good targets for cancer drugs; indeed, drugs targeting one such pathway (histone methyltransferases) are currently in pre-clinical development, while agents against another pathway (Hedgehog signaling pathway) are entering phase-2 clinical trials for medulloblastoma.
Cho is the co-chair of a committee within the Pediatric Brain Tumor Consortium that guides which drugs should be moved into clinical trials next. "Our plan is that within the next one to two years we will be able to offer kids a new set of compounds that have a clear biological rationale based on our genomic studies." Cho said. "We want to make sure we're being careful of what we move forward with, but at the same time, for some of these kids we don't have many, if any, effective and durable treatment options."
###
Stanford University Medical Center: http://med-www.stanford.edu/MedCenter/MedSchool
Thanks to Stanford University Medical Center for this article.
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Audio video software if just things you need if you are trying to enter into making videos and music videos. You cannot really do much with audio or videos by means of putting it all together for other people to see without some type of software program that allows you to edit and assembled a full video. With one of the newest trends on the net being video sites like YouTube, there are tons more people who are searching for some sort of software so they can join the craze and create their particular Internet.
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When you are looking for an audio video software it?s safer to do some research as there are tons of choices on the market nowadays. Visit some forums and consumer report websites to find out how people are reviewing the software?s that you are looking for purchasing.
You have bad credit. You may need a substantial infusion of greenbacks. Where would you go? Acquiring someone who would like to extend a long-term or maybe installment loan to you personally can be a challenge. However, acquiring a verifiable earnings that will allow you enough cash left over from your month-to-month expenses to spend such a loan, easy it really is.
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Is using credit charge cards a smart way in order to avoid college loan personal debt? Financial analysts are in near-universal arrangement that the answer is no, although that isn?t stopping thousands of individuals from using credit greeting cards in place of parent or guardian and student loans.
Basically, lots of people suffer from bad credit scores that you have lenders ready to give unsecured loans to these folks. Also, most lenders offer alternate loan options which do not even will need a credit check. Finding a loan with no credit check out is easy knowing the basic procedure.
When a college student is distracted by a bad credit background, a bad credit loans for students are usually an option how the Financial Aid professional can provide information on. They can be available at increased rates of interest, and then for longer terminology, but they provides the necessary cash to alleviate the economic pressures whilst studying.
In the event that none of the options are right for you and you are even now struggling with paying down your loans, you have to know that university student loans cannot normally be absolved by means of bankruptcy. In the event you come to here, a wage garnishment could be sought versus you simply by a creditor. A pay garnishment is a appropriate request that will seeks to look at money because payment through an worker?s salary. To avoid a wage garnishment you need to seek professional help from a bankruptcy lawyer. There is a safeguard against such creditor tactics, but you ought to speak with a legal professional in order to create a strategy within your defense.
The latest graduates typically face heavy debts, doing the pressure connected with finding full-time career acute. Obtaining one is difficult these days, therefore pay day loans online replacing provides a possible opportunity to improve the circumstances while they hop on their toes.
?Why won?t his or her look at the benefits of my company and not concentrate so much in this little personal credit which is my business that?ll be paying the loan back!?
It is only obvious that a credit rating should be known before attempting to negotiate a loan package ? though it is surprising exactly how few people truly try to find out the important points. So, before commencing an application with regard to a home equity loan with bad credit, have in mind the details of your credit score.
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Primary responsibilities include providing administrative support to the assigned investment managers. This may include correspondence, transcription, photocopying, mailing, faxing, filing, gathering and compiling reports for clients, per their requirements, and front desk relief for corporate receptionist.
ESSENTIAL FUNCTIONS:
Process and review Weekly reports from assigned sites.
Process and review bi-monthly payroll and commissions received from sites.
Review all received new hire paperwork for accuracy, and submit to payroll department.
Distribute monthly financial statements in format required by clients. Process quarterly funding requests, submit to bank, and track receipt of checks.
Complete any project assigned by investment manager.
Support the overall goals of the company by performing all other duties as assigned by direct supervisor.
QUALIFICATIONS: To perform this role successfully, an individual must be able to perform all essential functions satisfactorily. The requirements define the knowledge, skill, and/or ability necessary to perform the essential functions. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.
EDUCATION AND EXPERIENCE: Recent administrative related work experience required. Experience in the real estate management industry preferred.
LICENSE/CERTIFICATION: N/A
JOB KNOWLEDGE AND SKILLS: - Excellent organizational skills required. - Must be proficient in Microsoft Word and Excel. - Must be able to obtain proficiency in Yardi accounting software, Kronos automated timekeeping software and Groupwise email systems. - Must be able to communicate effectively, verbally and in writing, with internal and external customers in various positions of responsibility. -Must be able to consistently meet reporting deadlines.
Jim Thome is on the bench again today. He's receiving treatment for neck spasms, but he wouldn't have started anyway with the Orioles facing Oakland left-hander Travis Blackley.
